High doses of tranexamic acid were found to help control blood loss and reduce the need for transfusion in patients undergoing corrective spine surgery, especially those undergoing posterior vertebral column resection, according to researchers.
In a retrospective study, the researchers reviewed data for 59 patients between the ages of 7 years and 46 years with spinal deformities who underwent spinal corrective surgeries. Patients were categorized into one of two groups, with 26 patients who received tranexamic acid (TXA) in a treatment group and 33 patients who did not in a control group. Of those who received TXA, eight underwent posterior vertebral column resection (PVCR).
