By Casey Tingle
Local application of tranexamic acid plus diluted-epinephrine decreased postoperative blood loss and reduced the possibility of homologous blood transfusion following total knee arthroplasty, according to study results.
Researchers randomly assigned 100 patients undergoing total knee arthroplasty (TKA) for primary osteoarthritis of the knee to receive either tranexamic acid (TXA) plus diluted-epinephrine (DEP) or TXA alone.
