The collaboration gives tech startups the ability to demonstrate value directly with clinicians.
By Susan Morse , Executive Editor – October 15, 2025 –
Cleveland Clinic and Silicon Valley investor Khosla Ventures are collaborating to provide a direct health system pipeline to emerging technologies in areas such as artificial intelligence, digital health and next-generation therapeutics.
The collaboration includes agreements with Khosla-backed companies and identifying and incubating Cleveland Clinic research for the potential creation of new companies.
Cleveland Clinic said it has entered into customer agreements and commercial relationships with Khosla-backed companies and is evaluating several others.
As part of the collaboration, Khosla Ventures portfolio companies can work with Cleveland Clinic providers to showcase and test new technologies at all stages, from clinical validation to commercial adoption. This access gives startups the advantage of demonstrating value directly with clinicians and also accelerates scalable solutions.
Cleveland Clinic and Khosla Ventures are also exploring opportunities to jointly incubate a new company. Khosla Ventures will lead technical development and recruiting, while Cleveland Clinic plans to provide the clinical environment to test, refine and scale the service. No further information was given about the new company.
