By Laura Dyrda
A new study published in The Spine Journal reviews evidence-based orthopedics studies, identifying all randomized controlled trials that reported at least one positive outcome.
The researchers used Fisher’s exact test to compute the Fragility Index values and multivariable linear regression for associated factors.
There were 40 eligible randomized controlled trials with the average sample size of 132 patients and the average total chosen outcome events of 31. Here are five things to know from the report:
1. The average Fragility Index was two, indicating that adding two events to one of the trial’s treatment arms would eliminate the statistical significance.