NuVasive to Participate in Investor Events in June 2016

SAN DIEGO, CA –(Marketwired – May 31, 2016) – NuVasive, Inc. (NASDAQ: NUVA), a leading medical device company focused on transforming spine surgery with minimally disruptive, procedurally-integrated solutions, announced today that management will participate in the following investor events in June 2016:

• Goldman Sachs 37^th Annual Global Healthcare Conference at the Terranea Resort in Ranchos Palos Verdes, California on Tuesday, June 7, 2016 at 7:00 p.m. ET / 4:00 p.m. PT; and

• William Blair 36^th Annual Growth Stock Conference at the Four Seasons Hotel in Chicago, Illinois on Tuesday, June 14, 2016 at 12:30 p.m. ET / 9:30 a.m. PT.

A live webcast of the presentations will be available online from the Investor Relations page of the Company’s website at nuvasive.com. A replay of the presentations will remain available on the website for 30 days after the applicable live webcast.

About NuVasive

NuVasive, Inc. (NASDAQ: NUVA) is a world leader in minimally invasive, procedurally-integrated spine solutions. From complex spinal deformity to degenerative spinal conditions, NuVasive is transforming spine surgery with innovative technologies designed to deliver reproducible and clinically proven surgical outcomes. NuVasive’s highly differentiated procedurally-integrated solutions include access instruments, implantable hardware and software systems for surgical planning and reconciliation technology that centers on achieving the global alignment of the spine. With $811 million in revenues (2015), NuVasive has an approximate 1,600 person workforce in more than 40 countries around the world. For more information, please visit nuvasive.com.

NuVasive cautions you that statements included in this news release or made during the investor events announced herein that are not a description of historical facts are forward-looking statements that involve risks, uncertainties, assumptions and other factors which, if they do not materialize or prove correct, could cause NuVasive’s results to differ materially from historical results or those expressed or implied by such forward-looking statements. The potential risks and uncertainties which contribute to the uncertain nature of these statements include, among others, risks associated with the acceptance of the Company’s surgical products and procedures by spine surgeons, development and acceptance of new products or product enhancements, clinical and statistical verification of the benefits achieved via the use of NuVasive’s products (including the iGA™ platform), expansion of the Company’s network of sales representatives, and the other risks and uncertaintiesdescribed in NuVasive’s news releases and periodic filings with the Securities and Exchange Commission. NuVasive’s public filings with the Securities and Exchange Commission are available at www.sec.gov . NuVasive assumes no obligation to update any forward-looking statement to reflect events or circumstances arising after the date on which it was made.