Advancements and Projections in the Orthobiologics Market: Insights, Trends, Opportunities, and Recent Developments
New York, Nov. 11, 2024 (GLOBE NEWSWIRE) — Market Overview
Global Orthobiologics Market is projected to reach USD 7.1 billion by the end of 2024 and expand to USD 11.7 billion by 2033, with a CAGR of 5.7%.
Orthobiologics is a medical field that utilizes biological substances & materials to promote the healing and regeneration of musculoskeletal tissues. Treatments in this category include stem cell therapy, bone grafts, platelet-rich plasma (PRP), & viscosupplementation.
Orthobiologics are widely used in orthopedic surgeries & procedures to enhance recovery, alleviate pain, and improve functional outcomes in conditions such as osteoarthritis, tendon injuries, & spinal disorders. These products can be sourced from natural materials like bone, cartilage, or blood, or created through biotechnological processes.
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The US Orthobiologics Market
The U.S. orthobiologics market is expected to reach USD 3.0 billion by the end of 2024 and grow significantly to USD 4.8 billion by 2033, with an estimated CAGR of 5.4%. In 2024, the U.S. market is anticipated to account for 88.1% of the North American region.
The growth of the U.S. market is mainly driven by the aging population, which is increasingly affected by musculoskeletal disorders. Key trends in this region include the rising adoption of regenerative medicine techniques, such as platelet-rich plasma (PRP) and mesenchymal stem cells (MSCs).
Technological advancements and ongoing research are contributing to a continuous stream of improved orthobiologic products.
Important Insights
- Market Growth: The global orthobiologics market is anticipated to expand by USD 4.2 billion, achieving a compound annual growth rate (CAGR) of 5.7%.
- Market Definition: Orthobiologics refer to biological substances utilized in orthopedic treatments to accelerate the healing process of bones, muscles, ligaments, and tendons.
- Product Analysis: Supply Chain Management is projected to hold the largest revenue share at 45.2% by 2024.
- Application Analysis: The highway segment is expected to generate the highest revenue, contributing 51.5% of the market share by 2024.
- End User Analysis: Hospitals are predicted to lead in the end-user category, comprising 60.3% of the market’s revenue by 2024.
- Regional Analysis: North America is forecasted to dominate the global orthobiologics market with a 47.6% market share by 2024.
Latest Trends
- Advanced Imaging Techniques: Fluoroscopy and ultrasound have boosted the adoption of minimally invasive surgery (MIS) in orthopedics. These techniques improve visualization, leading to better surgical precision and faster recovery.
- Improved Outcomes: Using advanced imaging reduces complications during surgery, promoting quicker healing post-procedure. Orthobiologics play a crucial role in the rehabilitation process after MIS.
Competitive Landscape
- Innovative Growth Strategies: Key players in the orthobiologics market are expanding their product portfolios, forming strategic partnerships, and engaging in mergers and acquisitions to drive business growth.
- Strengthening Market Position: Companies are focusing on strategies like alliances, collaborations, geographic expansion, regulatory approvals, and launching new products to reinforce their presence in the market.
- Advancements in Regenerative Medicine: The orthobiologics sector plays a crucial role in advancing regenerative medicine, with leading players investing heavily in research and development to enhance market offerings.
- Competitive Market Dynamics: To remain competitive, companies like Integra LifeSciences, Medtronic Plc, and Stryker Corporation are focusing on innovation and offering affordable products to meet the evolving demands of the market.
Some of the prominent market players:
- Medtronic Plc
- DePuy Synthes
- Zimmer Biomet
- Stryker Corporation
- Bioventus LLC
- Anika Therapeutics, Inc.
- Orthofix, Inc.
- Globus Medical
- Arthrex, Inc.
- Bone Biologics Corp.
- Other Key Players
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Global Orthobiologics Market Scope
| Report Highlights | Details |
| Market Size (2024) | USD 7.1 Bn |
| Forecast Value (2033) | USD 11.7 Bn |
| CAGR (2024-2033) | 5.7% |
| North America Revenue Share | 47.6% |
| The US Market Size (2024) | USD 3.0 Bn |
| Historical Data | 2018 – 2023 |
| Forecast Data | 2025 – 2033 |
| Base Year | 2023 |
| Estimate Year | 2024 |
| Segments Covered | By Product, By Application, By End User |
| Regional Coverage | North America, Europe, Asia Pacific, Latin America, Middle East & Africa (MEA) |
Market Analysis
Among all segments, spinal fusion is expected to remain the largest segment, occupying 51.5% of the orthobiologics market share by 2024 because of rising cases of spinal ailments around the world. The main intention of spinal fusion surgery is to stop the spine from moving in a particular region by fusing it to offer it stability and increase the chances of eliminating chronic pain.
As more cases of spine ailments such as herniated discs, scoliosis, and spinal stenosis arise; there is a corresponding rise and need for spinal fusion surgery. Spinal fusions products like bone grafts, BMPs, and DBMs is common, as orthobiologics to support effective healing after fusion surgeries.
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Global Orthobiologics Market Segmentation
By Product
- Visco-supplementation
- Stem Cell Therapy
- Demineralized Bone Matrix (DBM)
- Allograft
- Bone Morphogenetic Protein (BMP)
- Synthetic Bone Substitutes
By Application
- Spinal Fusion
- Reconstructive Surgery
- Osteoarthritis and Degenerative Arthritis
- Trauma Repair
- Maxillofacial and Dental Applications
By End User
- Hospitals
- Orthopedic Clinics
- Ambulatory Care Centers
- Research and Academic Institutes
- Dental Clinics and Facilities
Drivers
- Increase in Spinal Disorder Cases: The rising prevalence of musculoskeletal diseases like osteoarthritis and degenerative disc disease drives the orthobiologics market, worsened by an aging population and more sports injuries.
- Role of Orthobiologics: Orthobiologics use natural substances to restore musculoskeletal tissues and offer minimally invasive treatments for faster recovery in spinal disorder patients.
- High Demand for Viscosupplements: Viscosupplements, hyaluronic acid-based injections for osteoarthritis, are increasingly preferred as a non-surgical treatment, especially among the elderly.
- Focus on Mobility and Quality of Life: The emphasis on mobility and quality of life for aging populations boosts the demand for viscosupplements, contributing to orthobiologics market growth.
Restraints
- Patient Preference for Non-Invasive Procedures: Growing patient preference for non-invasive treatments may hinder orthobiologics market growth, as more individuals opt for minimally invasive options over traditional therapies.
- Rising Costs of Orthobiologics Treatments: Increasing prices for orthobiologics treatments are expected to impede market growth, driven by complex synthesis processes, stringent manufacturing regulations, and high production costs.
Opportunities
- Increasing Cases of Road Accidents: The rise in global road accidents creates a significant opportunity for the orthobiologics market, with more orthopedic injuries requiring surgical interventions and rehabilitation.
- Obesity’s Impact on Orthopedic Disorders: Obesity is a major contributor to orthopedic issues, leading to increased stress on joints and conditions like osteoarthritis and joint pain.
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Regional Analysis
North America is expected to dominate the global orthobiologics market with 47.6% of the revenue in 2024 as the region has highly developed healthcare facilities, growing incidences of orthopedic conditions, and focused efforts towards the development of orthobiologics.
The region is known for common diseases including osteoarthritis, degenerative disc diseases, or sports-related traumas much of which will require orthobiologic products such as viscosupplements, stem cell therapies, or bone graft substitutes. There are more elderly people in both countries, and as a result, there is a need for treatments that will improve mobility, and reduce joint pains.
By Region
North America
- The U.S.
- Canada
Europe
- Germany
- The U.K.
- France
- Italy
- Russia
- Spain
- Benelux
- Nordic
- Rest of Europe
Asia-Pacific
- China
- Japan
- South Korea
- India
- ANZ
- ASEAN
- Rest of Asia-Pacific
Latin America
- Brazil
- Mexico
- Argentina
- Colombia
- Rest of Latin America
Middle East & Africa
- Saudi Arabia
- UAE
- South Africa
- Israel
- Egypt
- Rest of MEA
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Recent Developments
- November 2023: OssDsign AB announced a strategic pivot to focus solely on the U.S. orthobiologics market, positioning itself as a pure-play orthobiologics company. The company’s main focus will be on OssDsign Catalyst, a nanosynthetic bone graft product with over 90% gross margins, designed to stimulate healthy bone growth in spinal fusion surgeries and easily scalable.
- October 2023: Orthofix Medical Inc. launched OsteoCove, a bioactive synthetic graft that received 510(k) clearance for use in various orthopedic and spinal procedures.
- September 2023: NuVasive, Inc. merged with Globus Medical, Inc. to enhance their offering of musculoskeletal procedural solutions and technologies for both surgeons and patients.
- June 2023: Anika Therapeutics, Inc. secured additional 510(k) clearance from the U.S. FDA for its Tactoset Injectable Bone Substitute.
- March 2023: LifeNet Health introduced ViviGen MIS to the U.S. market, the first viable bone matrix to provide lineage-committed bone cells, specifically for use in minimally invasive spine surgeries.
- February 2022: Orthofix Medical Inc. launched Opus BA, a synthetic bone graft designed for lumbar and cervical spine fusions, available in strip and putty forms to fill bone gaps and voids in the skeletal system.
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