ExtremitiesSports MedicineUncategorized

Study: Healing outcomes after rotator cuff repair significantly improve with MSC therapy

LAS VEGAS — Use of bone marrow concentrate containing mesenchymal stem cells as an adjunct therapy showed significant improvement in healing outcomes after rotator cuff repair, according to data presented during the American Academy of Orthopaedic Surgeons Annual Meeting.

Researchers compared the outcomes of 45 patients who received concentrated bone marrow-derived mesenchymal stem cells (MSCs) as an adjunct to single-row rotator cuff repair at the time of arthroscopy with those of a control group of 45 patients matched for tear size and tendon rupture location, dominant shoulder, gender and age who did not receive MSCs. MRI postoperatively confirmed rotator cuff healing or retear at 3 months, 6 months, 1 year, 2 years and at the most recent follow-up.

Results showed non-healing or retear diagnosed on ultrasound and confirmed by MRI among 34% of shoulders. Between the tendons that healed and those that showed deficient healing or a frank retear, the researchers found no significant difference in preoperative cuff tear size at the time of screening or during surgery, with an estimated average cuff tear size of 2.3 cm in the healing group and of 2.2 cm in the group without healing.


Related Articles

Back to top button